Life Sci. J Rheumatol. Effects of estrogen on chondrocyte proliferation and collagen synthesis in skeletally mature articular cartilage.
J Appl Physiol. Frayling, John R. Despite this apparent sex dependency of GH secretion, to our knowledge there have been no studies on GH replacement in which gender has been considered in the evaluation of the outcome.
Characterizing the phenotypes of knockout models has advanced our understanding of the role of ER in biological processes.
As a child nears puberty, a gland in the brain, called the pituitary gland, increases the secretion of a hormone called follicle-stimulating hormone FSH. Characteristic pathological changes in OA not only include joint cartilage degeneration but also subchondral bone thickening, osteophyte formation and synovial inflammation, all of which are associated with capsule laxitude and decreased muscle strength [ 12 ].
Despite these studies, the influence of estrogen deficiency on cartilage remains unclear, even though there is significant evidence of the detrimental effect of estrogen loss in mature female animals [ 7 ]. Study of Osteoporotic Fractures Research Group.
All men received gonadal hormone replacement testosterone enanthate, mg, im, in two men every 2 weeks, in 7 men every 3 weeks, and in 9 men every 4 weeks. Published : 10 February Effect of rhGH on body composition and metabolic indexes before and after 9 months of treatment of 36 adults 21 men and 15 women with acquired GH deficiency.
Effects of estrogen and sex difference on secretion of human growth hormone.