The sequence data revealed expansions of gene families in the ruminant PAR region that have previously been associated with immune function, and conservation of gametologs that are known dosage sensitive regulators of gene expression. This inversion may correspond to an additional step extending further recombination cessation toward the PAR.
The genetic basis of this phenotypic variation is difficult to study, in part because we do not know the detailed organization of the Y chromosome. Open in new tab Download slide.
Oxford University Press, New York. Microbiology and Infectious Disease. TranslatorX: multiple alignment of nucleotide sequences guided by amino acid translations. Of the 11 genes in the cattle X-d1 region 8 are in common with horse and pig X-d1 regions, but the gene order differs between the three species.
Integrating Hi-C links with assembly graphs for chromosome-scaleassembly. MBio 6 : e Insights into epigenetic landscape of recombination-free regions.
We used alternative mating types isolated from a single diploid spore of M. E-mail: tim. Despite its critical role in fertility and disease, the PAR is one of the least well-characterised parts of most mammalian genomes. Selection on overdominant genes maintains heterozygosity along multiple chromosomes in a clonal lineage of honey bee.
Biol Lett 3 : — John B Cole. We also greatly expanded supporting RNA-based data for annotation that identifies 30, total genes 21, protein coding. Oxford University Press, New York. Biol Rev 86 : —